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October 06, 2025 l Issue #320

🔍 Top Insights

1. Sora 2 is here: a video generation model which is more physically accurate, realistic, and more controllable than prior systems
2. Seattle Children's Hospital implements Abridge's AI platform enterprise-wide
3. Launching Tinker, a flexible API for fine-tuning language models

The Big Unlock Podcast

Bridging the AI Gap in Healthcare with AI Literacy and Trust

With Jan Beger, Global Head of AI Advocacy at GE Healthcare

Learn more

Advancing AI to Transform Patient Care in Pharma

With Thomas Fuchs, Chief AI Officer at Eli Lilly

Learn more

Funding and M&A Moves

• Crystalys Therapeutics launches with $205 million funding round for trials of gout drug
• Privia acquires Evolent’s value-based primary care unit for $100M 

🤖 AI in Action

Use Case of the Week: Agentic AI for Call Management        

Health System: Raleigh Orthopaedic

Raleigh Orthopaedic deployed agentic AI to manage patient calls. The AI handles 38% of calls start-to-finish, reducing staff workload, wait times, and call abandonment. Integration with EHR and scheduling systems improved efficiency, allowing staff to focus on complex tasks and enhancing patient experience. 

📊 Industry Spotlight

1. Earning Trust for AI in Health: A Collaborative Path Forward
2. Physician practice acquisitions on the rise: GAO
3. How One Google Team Built Storytelling Into Analytics

🧠 Thought Leadership

• Why AI Literacy Matters for All Healthcare Staff: Clinical and Non-Clinical
• Harnessing AI to Transform Innovation in Pharma and Healthcare
• The Top 5 Real-World Problems Agentic Voice Agents Can Solve in Healthcare

📅 Upcoming Events

• State of Cybersecurity: Healthcare's Tactical Defense Summit - Oct 14, 2025 I Virtual
•  HLTH USA – Oct 19-22, 2025 I Las Vegas 

💬 From the Frontlines

“There is a massive technology transformation ahead of us, and a lot of people don’t even understand that this is coming and with quite some impact. 70% of job skills are expected to change by 2030, with AI driving much of this shift—not just in healthcare, but across different industries.”

— Jan Beger, Global Head of AI Advocacy at GE Healthcare (The Big Unlock Podcast Episode #183)

Open Jobs

• Technical Looker Developer and Consultant – GCP
• Senior Salesforce Developer
• Quality Assurance Engineer, Knowledge Informatics
• Business Analyst-Healthcare Integration

At Cleveland Clinic's AI Summit